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Zhang J, Thi Thanh Ha P, Lou Y, Hoogmartens J, van Schepdael A. Kinetic study of CYP3A4 activity on verapamil by capillary electrophoresis. J Pharm Biomed Anal 2005; 39:612-7.
Zhang J, Tian Q, Chan SY, Duan W, Zhou S. Insights into oxazaphosphorine resistance and possible approaches to its circumvention. Drug Resist Updat 2005; 8:271-97.
Zhang J, Tian Q, Zhu YZ, Xu AL, Zhou SF. Reversal of resistance to oxazaphosphorines. Curr Cancer Drug Targets 2006; 6:385-407.
Zhang J, Tran Q, Lattard V, Cashman JR. Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria. Pharmacogenetics 2003; 13:495-500.
Zhang J, Yin L, Liang G, Liu R, Fan K, Pu Y. Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese Population. Biomed Environ Sci 2011; 24:300-9.
Zhang J, Zhang D, McQuade JS, Behbehani M, Tsien JZ, Xu M. c-fos regulates neuronal excitability and survival. Nat Genet 2002; 30:416-20.
Zhang J, Zhou F, Wu X et al. 20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions. Drug Metab Dispos 2010; 38:2179-87.
Zhang JG, Dehal SS, Ho T et al. Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81. Drug Metab Dispos 2006; 34:734-7.
Zhang JG, Ho T, Callendrello AL, Crespi CL, Stresser DM. A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin. Drug Metab Lett 2010; 4:185-94.
Zhang JP, Lencz T, Malhotra AK. D2 receptor genetic variation and clinical response to antipsychotic drug treatment: A Meta-Analysis. Am J Psychiatry 2010; 167:763-72.
Zhang JP, Malhotra AK. Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction. Expert Opin Drug Metab Toxicol 2011; 7:9-37.
Zhang JW, Ge GB, Liu Y et al. Taxane’s substituents at C3’ affect its regioselective metabolism: different in vitro metabolism of cephalomannine and paclitaxel. Drug Metab Dispos 2008; 36:418-26.
Zhang JW, Liu Y, Cheng J et al. Inhibition of human liver cytochrome P450 by star fruit juice. J Pharm Pharm Sci 2007; 10:496-503.
Zhang JW, Liu Y, Li W, Hao DC, Yang L. Inhibitory effect of medroxyprogesterone acetate on human liver cytochrome P450 enzymes. Eur J Clin Pharmacol 2006; 62:497-502.
Zhang JW, Liu Y, Zhao JY et al. Metabolic profiling and cytochrome P450 reaction phenotyping of medroxyprogesterone acetate. Drug Metab Dispos 2008; 36:2292-8.
Zhang JY, Mi YJ, Chen SP et al. Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion. J Cell Biochem 2011; 112:1076-83.
Zhang K, Yang C, Xu Y et al. Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population. J Neural Transm 2010; 117:393-401.
Zhang L, Ding H, Yan J et al. Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population. Pharmacogenet Genomics 2008; 18:45-51.
Zhang L, Fitzloff JF, Engel LC, Cook CS. Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide. Xenobiotica 2001; 31:73-83.
Zhang L, Geng Y, Xiao N et al. High dietary n-6/n-3 PUFA ratio promotes HDL cholesterol level, but does not suppress atherogenesis in apolipoprotein E-null mice 1. J Atheroscler Thromb 2009; 16:463-71.
Zhang L, Huang X, Meng Z et al. Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration. Mol Endocrinol 2009; 23:137-45.
Zhang L, Liu SY, Chen Q, Shi QY, Zou H, Wu L. Association between polymorphisms of CYP17 and CYP3A4 genes and intrahepatic cholestasis of pregnancy in Chengdu. Sichuan Da Xue Xue Bao Yi Xue Ban 2006; 37:551-3, 582.
Zhang L, Mei Q, Li QS, Hu YM, Xu JM. The effect of cytochrome P2C19 and interleukin-1 polymorphisms on H. pylori eradication rate of 1-week triple therapy with omeprazole or rabeprazole, amoxycillin and clarithromycin in Chinese people. J Clin Pharm Ther 2010; 35:713-22.
Zhang L, Rothman N, Wang Y et al. Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene. Carcinogenesis 1998; 19:1955-61.
Zhang L, Weddle DL, Thomas P et al. Low levels of expression of cytochromes P-450 in normal and cancerous fetal pancreatic tissues of hamsters treated with NNK and/or ethanol. Toxicol Sci 2000; 56:313-23.
Zhang L, Yan Y, Zhu D et al. Nutlin-1 strengthened anti-proliferation and differentiation-inducing activity of ATRA in ATRA-treated p-glycoprotein deregulated human myelocytic leukemia cells. Invest New Drugs 2010. doi:10. 1007/s10637-010-9512-5.
Zhang L, Yang S, He YJ et al. Fluorouracil selectively enriches stem-like leukemic cells in a leukemic cell line. Int J Biol Sci 2010; 6:419-27.
Zhang LF, Hu X, Wang P, Zhang L. Metabolism of osthol in isolated hepatocytes of rat. Yao Xue Xue Bao 2009; 44:1131-5.
Zhang M, Ardlie K, Wacholder S, Welch R, Chanock S, O’Brien TR. Genetic variations in CC chemokine receptors and hypertension. Am J Hypertens 2006; 19:67-72.
Zhang M, Moore GA, Barclay ML, Begg EJ. Determination of perhexiline and its metabolite hydroxyperhexiline in human plasma by liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2009; 877:3025-30.
Zhang N, Kang TG, Yin HB. Optimal extraction of polysaccharide from Dioscorea nipponica by central composite design and response surface methodology. Zhong Yao Cai 2011; 34:123-6.
Zhang N, Shi YH, Hao CF et al. Association of +45G15G(T/G) and +276(G/T) polymorphisms in the ADIPOQ gene with polycystic ovary syndrome among Han Chinese women. Eur J Endocrinol 2008; 158:255-60.
Zhang PY, Wong IL, Yan CS et al. Design and syntheses of permethyl ningalin B analogues: potent multidrug resistance (MDR) reversal agents of cancer cells. J Med Chem 2010; 53:5108-20.
Zhang QX, Melnikov Z, Feierman DE. Characterization of the acetaminophen-induced degradation of cytochrome P450-3A4 and the proteolytic pathway. Basic Clin Pharmacol Toxicol 2004; 94:191-200.
Zhang QY, Dunbar D, Kaminsky L. Human cytochrome P-450 metabolism of retinals to retinoic acids. Drug Metab Dispos 2000; 28:292-7.
Zhang QY, Dunbar D, Ostrowska A, Zeisloft S, Yang J, Kaminsky LS. Characterization of human small intestinal cytochromes P-450. Drug Metab Dispos 1999; 27:804-9.
Zhang QY, Gu J, Su T et al. Generation and characterization of a transgenic mouse model with hepatic expression of human CYP2A6. Biochem Biophys Res Commun 2005; 338:318-24.
Zhang QY, Kaminsky LS, Dunbar D, Zhang J, Ding X. Role of small intestinal cytochromes p450 in the bioavailability of oral nifedipine. Drug Metab Dispos 2007; 35:1617-23.
Zhang R, Liu C, Wang N, Mi S. Determination of cytochrome P450 3A4 activity with testosterone probe using high performance liquid chromatography. Se Pu 2008; 26:80-3.
Zhang R, Sun J, Ma L et al. Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line. Toxicol Appl Pharmacol 2011; 252:18-27.
Zhang S, Song N, Li Q, Fan H, Liu C. Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 871:78-89.
Zhang T, Yong SL, Drinko JK et al. LQTS mutation N1325S in cardiac sodium channel gene SCN5A causes cardiomyocyte apoptosis, cardiac fibrosis and contractile dysfunction in mice. Int J Cardiol 2011; 147:239-45.
Zhang T, Zhu Y, Gunaratna C. Rapid and quantitative determination of metabolites from multiple cytochrome P450 probe substrates by gradient liquid chromatography-electrospray ionization-ion trap mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2002; 780:371-9.
Zhang W, Chan RJ, Chen H et al. Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia. J Biol Chem 2009; 284:22353-63.
Zhang W, Chang YZ, Kan QC et al. Association of human micro-opioid receptor gene polymorphism A118G with fentanyl analgesia consumption in Chinese gynaecological patients. Anaesthesia 2010; 65:130-5.
Zhang W, Chang YZ, Kan QC et al. CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients. Eur J Clin Pharmacol 2010; 66:61-6.
Zhang W, Deng S, Chen XP et al. Pharmacokinetics of rosuvastatin when coadministered with rifampicin in healthy males: a randomized, single-blind, placebo-controlled, crossover study. Clin Ther 2008; 30:1283-9.
Zhang W, Duan S, Kistner EO et al. Evaluation of genetic variation contributing to differences in gene expression between populations. Am J Hum Genet 2008; 82:631-40.
Zhang W, Gordon M, Schultheis AM et al. FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab. J Clin Oncol 2007; 25:3712-8.
Zhang W, Han F, Guo P et al. Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS-a high throughput approach to evaluate drug-drug interactions. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878:1169-77.
Zhang W, Kilicarslan T, Tyndale RF, Sellers EM. Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro. Drug Metab Dispos 2001; 29:897-902.
Zhang W, Konopleva M, Shi YX et al. Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. J Natl Cancer Inst 2008; 100:184-98.
Zhang W, Li J, Allen SM et al. Silencing the breast cancer resistance protein expression and function in caco-2 cells using lentiviral vector-based short hairpin RNA. Drug Metab Dispos 2009; 37:737-44.
Zhang W, Lim LY. Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro. Drug Metab Dispos 2008; 36:1283-90.
Zhang W, Lu D, Dong W et al. Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice. FEBS J 2011; 278:1484-92.
Zhang W, Purchio A, Chen K, Burns SM, Contag CH, Contag PR. In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors. Biochem Pharmacol 2003; 65:1889-96.
Zhang W, Purchio AF, Coffee R, West DB. Differential regulation of the human CYP3A4 promoter in transgenic mice and rats. Drug Metab Dispos 2004; 32:163-7.
Zhang W, Purchio AF, Chen K et al. A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene. Drug Metab Dispos 2003; 31:1054-64.
Zhang W, Ramamoorthy Y, Kilicarslan T, Nolte H, Tyndale RF, Sellers EM. Inhibition of cytochromes P450 by antifungal imidazole derivatives. Drug Metab Dispos 2002; 30:314-8.
Zhang W, Ramamoorthy Y, Tyndale RF, Sellers EM. Interaction of buprenorphine and its metabolite norbuprenorphine with cytochromes p450 in vitro. Drug Metab Dispos 2003; 31:768-72.
Zhang W, Shannon WD, Duncan J, Scheffer GL, Scheper RJ, McLeod HL. Expression of drug pathway proteins is independent of tumour type. J Pathol 2006; 209:213-9.
Zhang W, Yu BN, He YJ et al. Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males. Clin Chim Acta 2006; 373:99-103.
Zhang WV, D’Esposito F, Edwards RJ, Ramzan I, Murray M. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes. Drug Metab Dispos 2008; 36:2547-55.
Zhang WW, Zhang XJ, Liu HX et al. Cdk1 is required for the self-renewal of mouse embryonic stem cells. J Cell Biochem 2011; 112:942-8.
Zhang WX, Chen B, Jin Z et al. Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients. Xenobiotica 2008; 38:1422-36.
Zhang WY, Tu YB, Haining RL, Yu AM. Expression and functional analysis of CYP2D6. 24, CYP2D6. 26, CYP2D6. 27, and CYP2D7 isozymes. Drug Metab Dispos 2009; 37:1-4.
Zhang X, Chang H, Wiseman S et al. Bisphenol A disrupts steroidogenesis in human H295R cells. Toxicol Sci 2011; 121:320-7.
Zhang X, Jones DR, Hall SD. Prediction of the effect of erythromycin, diltiazem, and their metabolites, alone and in combination, on CYP3A4 inhibition. Drug Metab Dispos 2009; 37:150-60.
Zhang X, Lalezari JP, Badley AD et al. Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients. Clin Pharmacol Ther 2004; 75:558-68.
Zhang X, Li D, Duan S et al. Analysis of the association between Apolipoprotein D and schizophrenia. Neuropsychobiology 2006; 54:40-4.
Zhang X, Li L, Ding X, Kaminsky LS. Identification of cytochrome p450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose. Drug Metab Dispos 2011; 39:1433-9.
Zhang X, Liu P, Zhang B, Wang A, Yang M. Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells. Cancer Genet Cytogenet 2010; 197:46-53.
Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature 2007; 450:741-4.
Zhang X, Qiu F, Jiang J, Gao C, Tan Y. Intestinal absorption mechanisms of berberine, palmatine, jateorhizine, and coptisine: involvement of P-glycoprotein. Xenobiotica 2011; 41:290-6.
Zhang X, Quinney SK, Gorski JC, Jones DR, Hall SD. Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite. Drug Metab Dispos 2009; 37:1587-97.
Zhang X, Soong R, Wang K et al. Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. Biochem Cell Biol 2007; 85:337-46.
Zhang X, Wang Q, Neil B, Chen X. Effect of lycopene on androgen receptor and prostate-specific antigen velocity. Chin Med J 2010; 123:2231-6.
Zhang X, Wu X, Li J et al. MDR1 (multidrug resistence 1) can regulate GCS (glucosylceramide synthase) in breast cancer cells. J Surg Oncol 2011; 104:466-71.
Zhang X, Zhang QY, Liu D et al. Expression of cytochrome p450 and other biotransformation genes in fetal and adult human nasal mucosa. Drug Metab Dispos 2005; 33:1423-8.
Zhang XJ, Huang W, Yang S et al. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet 2009; 41:205-10.
Zhang XY, Tan YL, Zhou DF et al. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J Clin Psychopharmacol 2007; 27:246-51.
Zhang Y, Bao YL, Yang MT et al. Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells. Int J Biochem Cell Biol 2010; 42:1964-72.
Zhang Y, Chen CJ, Yang QL, Cheng LQ, Wang H, Huang LZ. Effect of interfering hepatocyte nuclear factor-1 alfa in HepG2 on the expressions of apoM, apoA-I and the correlative key enzyme of cholesterol metabolism. Zhonghua Gan Zang Bing Za Zhi 2011; 19:121-6.
Zhang Y, El-Sikhry H, Chaudhary KR et al. Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol 2009; 297:37-46.
Zhang Y, Emmanuel N, Kamboj G et al. PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X; 21)(p22; q22). Genes Chromosomes Cancer 2004; 40:365-70.
Zhang Y, Gaikwad NW, Olson K, Zahid M, Cavalieri EL, Rogan EG. Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. Metabolism 2007; 56:887-94.
Zhang Y, Guo X, Lin ET, Benet LZ. Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor. Drug Metab Dispos 1998; 26:360-6.
Zhang Y, Guo X, Lin ET, Benet LZ. In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes. Pharmacology 1999; 58:147-59.
Zhang Y, Klaassen CD. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice. J Lipid Res 2010; 51:3230-42.
Zhang Y, Klein K, Sugathan A et al. Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease. PLoS One 2011. doi:10. 1371/journal. pone. 0023506.
Zhang Y, Laterra J, Pomper MG. Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp. Neoplasia 2009; 11:96-101.
Zhang Y, Li H, Wang H et al. Syl611, a novel semisynthetic taxane derivative, reverses multidrug resistance by p-glycoprotein inhibition and facilitating inward transmembrane action. Cancer Chemother Pharmacol 2010; 66:851-9.
Zhang Y, Li M, Yao Q, Chen C. Roles and mechanisms of copper transporting ATPases in cancer pathogenesis. Med Sci Monit 2009; 15:1-5.
Zhang Y, Lin H. Quantum tunneling in testosterone 6beta-hydroxylation by cytochrome P450: reaction dynamics calculations employing multiconfiguration molecular-mechanical potential energy surfaces. J Phys Chem A 2009; 113:11501-8.
Zhang Y, Liu J. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and organic pollutants. J Hazard Mater 2011; 189:357-62.
Zhang Y, Luo Z, Ma L, Xu Q, Yang Q, Si L. Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation. Int J Mol Med 2010; 25:729-34.
Zhang Y, McGillicuddy FC, Hinkle CC et al. Adipocyte modulation of high-density lipoprotein cholesterol. Circulation 2010; 121:1347-55.
Zhang Y, Si D, Chen X et al. Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects. Br J Clin Pharmacol 2007; 64:67-74.
Zhang Y, Wang H, Wei L et al. Transcriptional modulation of BCRP gene to reverse multidrug resistance by toremifene in breast adenocarcinoma cells. Breast Cancer Res Treat 2010; 123:679-89.
Zhang Y, Zanotti I, Reilly MP et al. Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo. Circulation 2003; 108:661-3.
Zhang Y, Zhao T, Li W, Vore M. The 5’-untranslated region of multidrug resistance associated protein 2 (MRP2; ABCC2) regulates downstream open reading frame expression through translational regulation. Mol Pharmacol 2010; 77:237-46.
Zhang Y, Zhong D, Si D, Guo Y, Chen X, Zhou H. Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype. Br J Clin Pharmacol 2005; 59:14-7.
Zhang YY, Liu Y, Zhang JW et al. Characterization of human cytochrome P450 isoforms involved in the metabolism of 7-epi-paclitaxel. Xenobiotica 2009; 39:283-92.
Zhang YY, Xie KM, Yang GQ et al. The effect of glucosylceramide synthase on P-glycoprotein function in K562/AO2 leukemia drug-resistance cell line. Int J Hematol 2011; 93:361-7.
Zhang Z, Deng X, Ren X et al. Expression of mutant p53 and of the multidrug resistant proteins P-glycoprotein and glutathione S-transferase-pi correlated in colorectal adenocarcinoma. Scand J Gastroenterol 2010; 45:925-34.
Zhang Z, Hartmann H, Minh Do V et al. Destabilization of beta-catenin bby mutations in presenilin-1 potentiates neuronal apoptosis. Nature 1998; 395:698-702.
Zhang Z, Li Y, Shou M et al. Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4. Xenobiotica 2004; 34:473-86.
Zhang Z, Li Y, Stearns RA, Ortiz de Montellano PR, Baillie TA, Tang W. Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil. Biochemistry 2002; 41:2712-8.
Zhang ZJ, Zhang XB, Hou G, Yao H, Reynolds GP. Interaction between polymorphisms of the dopamine D3 receptor and manganese superoxide dismutase genes in susceptibility to tardive dyskinesia. Psychiatr Genet 2003; 13:187-92.
Zhang ZY, Chen M, Chen J, Padval MV, Kansra VV. Biotransformation and in vitro assessment of metabolism-associated drug-drug interaction for CRx-102, a novel combination drug candidate. J Pharm Biomed Anal 2009; 50:200-9.
Zhang ZY, King BM, Mollova NN, Wong YN. In vitro interactions between a potential muscle relaxant E2101 and human cytochromes P450. Drug Metab Dispos 2002; 30:805-13.
Zhang ZY, King BM, Pelletier RD, Wong YN. Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4. Cancer Chemother Pharmacol 2008; 62:707-16.
Zhang ZY, Wong YN. Enzyme kinetics for clinically relevant CYP inhibition. Curr Drug Metab 2005; 6:241-57.
Zhao AY, Wang XD, Chen GH, Lu LZ. Low-level expression of cholesterol 7 α-hydroxylase is associated with the formation of goose fatty liver. Poult Sci 2011; 90:1045-9.
Zhao F, Loke C, Rankin SC et al. Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose. Clin Pharmacol Ther 2004; 76:210-9.
Zhao F, Wang J, Yang Y et al. Effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter pylori eradication: a meta-analysis. Helicobacter 2008; 13:532-41.
Zhao G, Allis JW. Kinetics of bromodichloromethane metabolism by cytochrome P450 isoenzymes in human liver microsomes. Chem Biol Interact 2002; 140:155-68.
Zhao H, Yao Y, Wang Z, Lin F, Sun Y, Chen P. Therapeutic effect of pirarubicin-based chemotherapy for osteosarcoma patients with lung metastasis. J Chemother 2010; 22:119-24.
Zhao J, Leemann T, Dayer P. In vitro oxidation of oxicam NSAIDS by a human liver cytochrome P450. Life Sci 1992; 51:575-81.
Zhao L, Jin X, Xu Y et al. Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1. J Exp Clin Cancer Res 2010; 29:98.
Zhao L, Moos MPW, Grabner R et al. The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. Nat Med 2004; 10:966-73.
Zhao L-X, Zhou C-J, Tanaka A et al. Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2. Biochem J 2000; 350:865-72.
Zhao M, Li LP, Shen J, Jiang HD. Inhibitory and inductive effects of (-)- and (+)-tetrahydropalmatine on CYP450 in mice. Zhejiang Da Xue Xue Bao Yi Xue Ban 2011; 40:33-9.
Zhao Q, Gu D, Kelly TN et al. Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt study. Am J Hypertens 2010; 23:606-13.
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Zhao Q, Zhang H, Li Y, Liu J, Hu X, Fan L. Anti-tumor effects of CIK combined with oxaliplatin in human oxaliplatin-resistant gastric cancer cells in vivo and in vitro. J Exp Clin Cancer Res 2010; 29:118.
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Zhao W, Elie V, Roussey G et al. Population pharmacokinetics and pharmacogenetics of tacrolimus in de novo pediatric kidney transplant recipients. Clin Pharmacol Ther 2009; 86:609-18.
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Zhao XJ, Koyama E, Ishizaki T. An in vitro study on the metabolism and possible drug interactions of rokitamycin, a macrolide antibiotic, using human liver microsomes. Drug Metab Dispos 1999; 27:776-85.
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Zhao YX, Liang WQ, Wang Y, Liu DX. Cationic submicron emulsions overcome multidrug resistance in SGC7901/VCR cells. Pharmazie 2011; 66:130-5.
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Zhao Z, Koeplinger KA, Waldon DJ. Stereoselective hydroxylation of nonpeptidic HIV protease inhibitors by CYP2D6. Chirality 1999; 11:731-9.
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Zhou GB, Zhang J, Wang ZY, Chen SJ, Chen Z. Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. Philos Trans R Soc Lond B Biol Sci 2007; 362:959-71.
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Zhou H, Gurley EC, Jarujaron S et al. HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes. Am J Physiol Gastrointest Liver Physiol 2006; 291:1071-80.
Zhou H, Jungbluth H, Sewry CA et al. Molecular mechanisms and phenotypic variation in RYR1-related congenital myopathies. Brain 2007; 130:2024-36.
Zhou J, Cai ZH, Zhu XS, Li L, Gao YF. Innate immune parameters and haemolymph protein expression profile to evaluate the immunotoxicity of tributyltin on abalone (Haliotis diversicolor supertexta). Dev Comp Immunol 2010; 34:1059-67.
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Zhou J, Liu M, Zhai Y, Xie W. The antiapoptotic role of pregnane X receptor in human colon cancer cells. Mol Endocrinol 2008; 22:868-80.
Zhou J, Lu Y, Gao XH et al. The growth hormone receptor gene is associated with mandibular height in a Chinese population. J Dent Res 2005; 84:1052-6.
Zhou J, Wang Y, Chen Z, Gao Y. Modulation of activities and mRNA expression of cytochrome P450 isoenzymes in rat liver by Sophora flaveacens and coadministration with Veratrum nigrum. Zhongguo Zhong Yao Za Zhi 2010; 35:1845-9.
Zhou JB, Yang JK. Meta-analysis of association of ACE2 G8790A polymorphism with Chinese Han essential hypertension. J Renin Angiotensin Aldosterone Syst 2009; 10:31-4.
Zhou JS, Xing W, Friend DS, Austen KF, Katz HR. Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis. J Exp Med 2007; 204:2797-802.
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Zhou L, Yan T, Jiang Y et al. Prognostic and predictive value of TFF1 for adjuvant endocrine therapy in Chinese women with early ER positive breast cancer: comparing aromatase inhibitors with tamoxifen. Breast 2011; 20:15-20.
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Zhou Q, Yao TW, Yu YN, Zeng S. Stereoselective metabolism of propafenone by human liver CYP3A4 expressed in transgenic Chinese hamster CHL cells lines. Acta Pharmacol Sin 2001; 22:944-8.
Zhou Q, Yao TW, Zeng S. Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers. World J Gastroenterol 2001; 7:830-5.
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Zhou S, Paxton JW, Tingle MD, Kestell P. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid. Drug Metab Dispos 2000; 28:1449-56.
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Zhou TB, Qin YH, Lei FY, Su LN, Zhao YJ, Huang WF. apoE expression in glomerulus and correlation with glomerulosclerosis induced by adriamycin in rats. Ren Fail 2011; 33:348-54.
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Zhou X, Lee JE, Arnett FC et al. HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. Arthritis Rheum 2009; 60:3807-14.
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Zhou Y, Abidi P, Kim A et al. Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceridemia through enhanced beta-oxidation. Arterioscler Thromb Vasc Biol 2007; 27:2198-205.
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Zhu W, Wang L, Zhang L et al. Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice. Neuroscience 2010; 169:758-69.
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