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Wang B, Sánchez RI, Franklin RB, Evans DC, Huskey SE. The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiol. Drug Metab Dispos 2004; 32:1209-12.

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Wang CY, Zhong WB, Chang TC, Lai SM, Tsai YF. Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells. J Clin Endocrinol Metab 2003; 88:3021-6.

Wang CH, Wu KH, Yang YL et al. Association study of cyclooxygenase 2 single nucleotide polymorphisms and childhood acute lymphoblastic leukemia in Taiwan. Anticancer Res 2010; 30:3649-53.

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Wang F, He Y, Guo H et al. Genetic variants of nucleotide excision repair genes are associated with DNA damage in coke oven workers. Cancer Epidemiol Biomarkers Prev 2010; 19:211-8.

Wang F, Liang YJ, Wu XP et al. Prognostic value of the multidrug resistance transporter ABCG2 gene polymorphisms in Chinese patients with de novo acute leukaemia. Eur J Cancer 2011; 47:1990-9.

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Wang F, Okamoto Y, Inoki I et al. Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J Clin Invest 2010; 120:3979-95.

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Wang F, Zhou F, Kruh GD, Gallo JM. Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors. Neuro Oncol 2010; 12:1043-9.

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Wang G, Rong J, Zhou Z, Duo J. Novel gene P28GANK confers multidrug resistance by modulating the expression of MDR-1, Bcl-2 and Bax in osteosarcoma cells. Mol Biol 2010; 44:1010-7.

Wang G, Xiao CQ, Li Z et al. Effect of soy extract administration on losartan pharmacokinetics in healthy female volunteers. Ann Pharmacother 2009; 43:1045-9.

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Wang GJ, Chang L, Volkow ND et al. Decreased brain dopaminergic transporters in HIV-associated dementia patients. Brain 2004; 127:2452-8.

Wang H, An N, Wang H et al. Evaluation of the effects of 20 nonsynonymous single nucleotide polymorphisms of CYP2C19 on S-mephenytoin 4’-hydroxylation and omeprazole 5’-hydroxylation. Drug Metab Dispos 2011; 39:830-7.

Wang H, Bian T, Liu D et al. Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes. Pharmacogenomics 2011; 12:481-92.

Wang H, Ding K, Zhang Y, Jin L, Kullo IJ, He F. Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions. Pharmacogenet Genomics 2007; 17:667-78.

Wang H, Goland S, Burton K, Czer LS, Schwarz ER, Trento A. An agonist of liver X receptor slows valvular disease in a hypercholesterolemia mouse model. J Heart Valve Dis 2010; 19:653-64.

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Wang H, Jin G, Wang H et al. Genetic susceptibility of lung cancer associated with common variants in the 3’ untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export. Cancer 2009; 115:595-607.

Wang H, Kim RA, Sun D et al. Evaluation of the effects of 18 non-synonymous single-nucleotide polymorphisms of CYP450 2C19 on in vitro drug inhibition potential by a fluorescence-based high-throughput assay. Xenobiotica 2011; 41:826-35.

Wang H, LeCluyse EL. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes. Clin Pharmacokinet 2003; 42:1331-57.

Wang H, Lee EW, Zhou L et al. Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells. Mol Pharmacol 2008; 73:845-54.

Wang H, Leung LK. The carotenoid lycopene differentially regulates phase I and II enzymes in dimethylbenz[a]anthracene-induced MCF-7 cells. Nutrition 2010; 26:1181-7.

Wang H, Li H, Moore LB et al. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Mol Endocrinol 2008; 22:838-57.

Wang H, Li Q, Wang T et al. A common polymorphism in the human aromatase gene alters the risk for polycystic ovary syndrome and modifies aromatase activity in vitro. Mol Hum Reprod 2011; 17:386-91.

Wang H, Negishi M. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors. Curr Drug Metab 2003; 4:515-25.

Wang H, Tompkins LM. CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme. Curr Drug Metab 2008; 9:598-610.

Wang H, Wang L, Erdjument-Bromage H et al. Role of histone H2A ubiquitination in Polycomb silencing. Nature 2004; 431:873-8.

Wang H, Yamamoto JF, Caberto C et al. Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. Carcinogenesis 2011; 32:203-9.

Wang H, Yuan L, Zeng S. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. Biochem Pharmacol 2011. doi:10. 1016/j. bcp. 2011. 08. 004.

Wang HH, Liao YW, Chiang HL, Wu JY, Chen YT. Novel DNA sequence variations of cytochrome P450 genes in the Han Chinese population. Pharmacogenomics 2009; 10:359-74.

Wang HL, Lopategui J, Amin MB, Patterson SD. KRAS mutation testing in human cancers: The pathologist’s role in the era of personalized medicine. Adv Anat Pathol 2010; 17:23-32.

Wang J. CYP3A polymorphisms and immunosuppressive drugs in solid-organ transplantation. Expert Rev Mol Diagn 2009; 9:383-90.

Wang J, Ban MR, Kennedy BA et al. APOA5 genetic variants are markers for classic hyperlipoproteinemia phenotypes and hypertriglyceridemia. Nat Clin Pract Cardiovasc Med 2008; 5:730-7.

Wang J, Freeman DJ, Grundy SM, Levine DM, Guerra R, Cohen JC. Linkage between cholesterol 7-alpha-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations. J Clin Invest 1998; 101:1283-91.

Wang J, Gao QS, Wang Y, Lafyatis R, Stamm S, Adreadis A. Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricated interplay of cis elements and trans factors. J Neurochem 2004; 88:1078-90.

Wang J, Hu Y, Nekvindova J, Ingelman-Sundberg M, Neve EP. IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways. Biochem Pharmacol 2010; 80:1592-600.

Wang J, Joshi AD, Corral R et al. Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. Int J Cancer 2011. doi:10. 1002/ijc. 26199.

Wang J, Lippman SM, Lee JJ et al. Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma. Carcinogenesis 2010; 31:1755-61.

Wang J, Nuite M, McAlindon TE. Association of estrogen and aromatase gene polymorphisms with systemic lupus erythematosus. Lupus 2010; 19:734-40.

Wang J, Qu H, Jin L et al. Pegylated phosphotidylethanolamine inhibiting P-glycoprotein expression and enhancing retention of doxorubicin in MCF7/ADR cells. J Pharm Sci 2011; 100:2267-77.

Wang J, Shi X, Du Y, Zhou B. Effects of xenoestrogens on the expression of vitellogenin (vtg) and cytochrome P450 aromatase (cyp19a and b) genes in zebrafish (Danio rerio) larvae. J Environ Sci Health A Tox Hazard Subst Environ Eng 2011; 46:960-7.

Wang J, Sönnerborg A, Rane A et al. Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz. Pharmacogenet Genomics 2006; 16:191-8.

Wang J, Spitz MR, Amos CI, Wilkinson AV, Wu X, Shete S. Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk. Cancer 2010; 116:3458-62.

Wang J, Tang S, Shen H. Association of genetic polymorphisms in the IL12-IFNG pathway with susceptibility to and prognosis of pulmonary tuberculosis in a Chinese population. Eur J Clin Microbiol Infect Dis 2010; 29:1291-5.

Wang J, Wang B, Bi J. Significant association between ABCB1 gene C3435T polymorphism and breast cancer risk. Breast Cancer Res Treat 2011; 126:815-7.

Wang J, Wang B, Bi J, Di J. The association between two polymorphisms in the TYMS gene and breast cancer risk: a meta-analysis. Breast Cancer Res Treat 2011; 128:203-9.

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Wang J, Zhao Y, Jiang J et al. Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case-control study in an Indian population. J Cancer Res Clin Oncol 2010; 136:1517-25.

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Wang JS, Backman JT, Wen X, Taavitsainen P, Neuvonen PJ, Kivistö KT. Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. Pharmacol Toxicol 1999; 85:201-5.

Wang JS, DeVane CL. Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro. Drug Metab Dispos 2003; 31:742-7.

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Wang JS, Hu XY, Zhang W, Yuan J, Yang Y, Fang Q. Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects. Zhonghua Yi Xue Za Zhi 2010; 90:2130-5.

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Wang JS, Wang W, Xie HG, Huang SL, Zhou HH. Effect of troleandomycin on the pharmacokinetics of imipramine in Chinese: the role of CYP3A. Br J Clin Pharmacol 1997; 44:195-8.

Wang JS, Wen X, Backman JT, Taavitsainen P, Neuvonen PJ, Kivistö KT. Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole. Pharmacol Toxicol 1999; 85:157-61.

Wang JS, Zhu HJ, Markowitz JS, Donovan JL, DeVane CL. Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein. Psychopharmacology 2006; 187:415-23.

Wang K, Chen S, Xie W, Wan YJ. Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway. Biochem Pharmacol 2008; 75:2204-13.

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Wang KS, Mullersman JE, Liu XF. Family-based association analysis of the MAPT gene in Parkinson disease. Appl Genet 2010; 51:509-14.

Wang KY, Tanimoto A, Guo X et al. Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level. Arterioscler Thromb Vasc Biol 2011; 31:800-7.

Wang L, Christopher LJ, Cui D et al. Identification of the human enzymes involved in the oxidative metabolism of dasatinib: an effective approach for determining metabolite formation kinetics. Drug Metab Dispos 2008; 36:1828-39.

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Wang L, Xu J, Ji C et al. Cloning, expression and characterization of human glutathione S-transferase Omega 2. Int J Mol Med 2005; 16:19-27.

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Wang L, Yin F, Du Y et al. Depression of MAD2 inhibits apoptosis and increases proliferation and multidrug resistance in gastric cancer cells by regulating the activation of phosphorylated survivin. Tumour Biol 2010; 31:225-32.

Wang L, Yu L, Zhang AP et al. Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia. J Psychopharmacol 2007; 21:837-42.

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Wang LH, Peck RW, Yin Y, Allanson J, Wiggs R, Wire MB. Phase I safety and pharmacokinetic trials of 1263W94, a novel oral anti-human cytomegalovirus agent, in healthy and human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother 2003; 47:1334-42.

Wang LQ, James MO. Inhibition of sulfotransferases by xenobiotics. Curr Drug Metab 2006; 7:83-104.

Wang LS, Zhou G, Zhu B et al. St John’s wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole. Clin Pharmacol Ther 2004; 75:191-7.

Wang LZ, Tian Y, Yu JT et al. Association between late-onset Alzheimer’s disease and microsatellite polymorphisms in intron II of the human toll-like receptor 2 gene. Neurosci Lett 2011; 489:164-7.

Wang LZ, Yu JT, Miao D et al. Genetic association of TLR4/11367 polymorphism with late-onset Alzheimer’s disease in a Han Chinese population. Brain Res 2011; 1381:202-7.

Wang M, Chen M, Zheng G et al. Transcriptional activation by growth hormone of HNF-6-regulated hepatic genes, a potential mechanism for improved liver repair during biliary injury in mice. Am J Physiol Gastrointest Liver Physiol 2008; 295:357-66.

Wang M, Gao M, Miller KD, Sledge GW, Hutchins GD, Zheng QH. Synthesis of carbon-11-labeled casimiroin analogues as new potential PET agents for imaging of quinone reductase 2 and aromatase expression in breast cancer. Steroids 2010; 75:967-73.

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Wang MZ, Saulter JY, Usuki E et al. CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]. Drug Metab Dispos 2006; 34:1985-94.

Wang MZ, Wu JQ, Bridges AS et al. Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine. Drug Metab Dispos 2007; 35:2067-75.

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Wang N, Tsuruoka S, Yamamoto H et al. The bioreactor with CYP3A4- and glutamine synthetase-introduced HepG2 cells: treatment of hepatic failure dog with diazepam overdosage. Artif Organs 2005; 29:681-4.

Wang P, Koehle MS, Rupert JL. Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness. High Alt Med Biol 2009; 10:261-7.

Wang P, Mao Y, Razo J et al. Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients. Pharmacogenomics 2010; 11:1389-402.

Wang P, Tang JT, Peng YS, Chen XY, Zhang YJ, Fang JY. XRCC1 downregulated through promoter hypermethylation is involved in human gastric carcinogenesis. J Dig Dis 2010; 11:343-51.

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Wang Q, Li H, Tao P et al. Soy isoflavones, CYP1A1, CYP1B1, and COMT polymorphisms, and breast cancer: A case-control study in Southwestern China. DNA Cell Biol 2011; 30:585-95.

Wang Q, Wang YP, Li JY, Yuan P, Yang F, Li H. Polymorphic catechol-O-methyltransferase gene, soy isoflavone intake and breast cancer in postmenopausal women: a case-control study. Chin J Cancer 2010; 29:683-8.

Wang Q, Zhao H, Xiang Q et al. Effect of Yikun Neiyi Wan on the expression of aromatase P450, COX-2, and ER related receptor in endometrial cells in vitro from patients with endometriosis. J Tradit Chin Med 2009; 29:296-300.

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Wang RW, Newton DJ, Scheri TD, Lu AY. Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis. Drug Metab Dispos 1997; 25:502-7.

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Wang X, Cheung CM, Lee WY, Or PM, Yeung JH. Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro. Phytomedicine 2010; 17:868-75.

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Wang X, Goode EL, Fredericksen ZS et al. Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2008; 17:2101-8.

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Wang X, Hawkins BT, Miller DS. Activating PKC-β1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS. J Cereb Blood Flow Metab 2011; 31:1371-5.

Wang X, Imura T, Sofroniew MV, Fushiki S. Loss of adenomatous polyposis coli in Bergmann glia disrupts their unique architecture and leads to cell nonautonomous neurodegeneration of cerebellar Purkinje neurons. Glia 2011; 59:857-68.

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Wang Y, Ao H, Qian Z, Zheng Y. Intestinal transport of scutellarein and scutellarin and first-pass metabolism by UDP-glucuronosyltransferase-mediated glucuronidation of scutellarein and hydrolysis of scutellarin. Xenobiotica 2011; 41:538-48.

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