General References

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B

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Babalola CP, Adejumo O, Ung D et al. Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls. J Clin Pharm Ther 2010; 35:471-7.

Babalola CP, Kolade YT, Olaniyi AA, Adedapo A, Scriba GK. Effect of fluconazole on the pharmacokinetics of halofantrine in healthy volunteers. J Clin Pharm Ther 2009; 34:677-82.

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Babaoglu MO, Yasar U, Sandberg M et al. CYP2C9 genetic variants and losartan oxidation in a Turkish population. Eur J Clin Pharmacol 2004; 60:337-42.

Babbar S, Chanda S, Bley K. Inhibition and induction of human cytochrome P450 enzymes in vitro by capsaicin. Xenobiotica 2010; 40:807-16.

Babenko AP, Polak M, Cavé H et al. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med 2006; 355:456-66.

Babić Z, Kucisec-Tepes N, Troskot R, Dorosulić Z, Svoboda-Beusan I. The importance of P-glycoprotein multidrug transporter activity measurement in patients with Helicobacter pylori infection. Coll Antropol 2009; 33:1145-50.

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Babron MC, Nilsson S, Adamovic S et al. Meta and pooled analysis of European coeliac disease data. Eur J Hum Genet 2003; 11:828-34.

Babu E, Takeda M, Narikawa S et al. Human organic anion transporters mediate the transport of tetracycline. Jpn J Pharmacol 2002; 88:69-76.

Baccarelli A, Calista D, Minghetti P et al. XPD gene polymorphism and host characteristics in the association with cutaneous malignant melanoma risk. Br J Cancer 2004; 90:497-502.

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Backman JT, Granfors MT, Neuvonen PJ. Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine. Eur J Clin Pharmacol 2006; 62:451-61.

Backman JT, Kyrklund C, Kivistö KT, Wang JS, Neuvonen PJ. Plasma concentrations of active simvastatin acid are increased by gemfibrozil. Clin Pharmacol Ther 2000; 68:122-9.

Backman JT, Mäenpää J, Belle DJ, Wrighton SA, Kivistö KT, Neuvonen PJ. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; 67:382-90.

Backman JT, Olkkola KT, Neuvonen PJ. Rifampin drastically reduces plasma concentrations and effects of oral midazolam. Clin Pharmacol Ther 1996; 59:7-13.

Backman JT, Wang JS, Wen X, Kivistö KT, Neuvonen PJ. Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam. Clin Pharmacol Ther 1999; 66:401-7.

Bacher I, Wu B, Shytle DR, George TP. Mecamylamine – a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opin Pharmacother 2009; 10:2709-21.

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Bachleda P, Vrzal R, Pivnicka J, Cvek B, Dvorak Z. Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes. Toxicol Lett 2009; 191:74-8.

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Bachman ES, Dhillon H, Zhang CY et al. Beta-AR signaling required for diet-induced thermogenesis and obesity resistance. Science 2002; 297:843-5.

Bachmann K, He Y, Sarver JG, Peng N. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes. Xenobiotica 2003; 33:265-76.

Bachmann K, Jauregui L, Chandra R, Thakker K. Influence of a 3-day regimen of azithromycin on the disposition kinetics of cyclosporine A in stable renal transplant patients. Pharmacol Res 2003; 47:549-54.

Bachmeier C, Beaulieu-Abdelahad D, Mullan M, Paris D. Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier. Eur J Pharmacol 2011; 659:124-9.

Bachmeier CJ, Beaulieu-Abdelahad D, Ganey NJ, Mullan MJ, Levin GM. Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine. Biopharm Drug Dispos 2011; 32:233-44.

Bachus R, Bickel U, Thomsen T, Roots I, Kewitz H. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics 1999; 9:661-8.

Badagnani I, Castro RA, Taylor TR et al. Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J Pharmacol Exp Ther 2006; 318:521-9.

Badal S, Williams SA, Huang G et al. Cytochrome P450 1 enzyme inhibition and anticancer potential of chromene amides from Amyris plumieri. Fitoterapia 2011; 82:230-6.

Badaracco MA. Keeping our depressed patients in the right treatment long enough for them to get better: some hopeful findings. Am J Psychiatry 2007; 164:1136-9.

Badawi AF, Cavalieri EL, Rogan EG. Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol. Metabolism 2001; 50:1001-3.

Bader A, Hansen T, Kirchner G, Allmeling C, Haverich A, Borlak JT. Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions. Br J Pharmacol 2000; 129:331-42.

Bader MI, Wober J, Kretzschmar G, Zierau O, Vollmer G. Comparative assessment of estrogenic responses with relevance to the metabolic syndrome and to menopausal symptoms in wild-type and aromatase-knockout mice. J Steroid Biochem Mol Biol 2011. doi:10. 1016/j. jsbmb. 2011. 05. 004.

Badruddin A, Gorelick PB. Antiplatelet therapy for prevention of recurrent stroke. Curr Treat Options Neurol 2009; 11:452-9.

Badyal DK, Dadhich AP. Cytochrome P450 and drug interactions. Indian J of Pharmacol 2001; 33:248-59.

Bae JW, Choi CI, Jang CG, Lee SY. Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam. Br J Clin Pharmacol 2011; 71:550-5.

Bae JW, Choi CI, Kim MJ et al. Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics. Acta Pharmacol Sin 2011; 32:1303-8.

Bae JW, Choi CI, Lee JH, Jang CG, Chung MW, Lee SY. Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. Eur J Clin Pharmacol 2011; 67:39-45.

Bae JW, Jang CG, Lee SY. Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites. J Clin Pharmacol 2011. doi:10. 1177/0091270010388651.

Bae JW, Kim JH, Choi CI et al. Effect of CYP2C9*3 allele on the pharmacokinetics of naproxen in Korean subjects. Arch Pharm Res 2009; 32:269-73.

Bae SH, Bae SK, Lee MG. Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo. J Pharm Pharmacol 2009; 61:1637-42.

Bae SH, Sung SH, Cho EJ et al. Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver. Hepatology 2011; 53:945-53.

Bae SK, Cao S, Seo KA et al. Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes. Drug Metab Dispos 2008; 36:1679-88.

Baede-van Dijk PA, Hugen PW, Verweij-van Wissen CP, Koopmans PP, Burger DM, Hekster YA. Analysis of variation in plasma concentrations of nelfinavir and its active metabolite M8 in HIV-positive patients. AIDS 2001; 15:991-8.

Baede-van Dijk PA, van Galen E, Lekkerkerker JF. Drug interactions of Hypericum perforatum (St. John’s wort) are potentially hazardous. Ned Tijdschr Geneeskd 2000; 144:811-2.

Baek MS, Kim JY, Myung SW, Yim YH, Jeong JH, Kim DH. Metabolism of dimethyl-4,4’-dimethoxy-5,6,5’,6’-dimethylene dioxybiphenyl-2,2’-dicarboxylate (DDB) by human liver microsomes: characterization of metabolic pathways and of cytochrome P450 isoforms involved. Drug Metab Dispos 2001; 29:381-8.

Baek SH, Ohgi KA, Rose DW, Koo EH, Glass CK, Rosenfeld MG. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappa-B and beta-amyloid precursor protein. Cell 2002; 110:55-67.

Baer BR, Rettie AE, Henne KR. Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate. Chem Res Toxicol 2005; 18:855-64.

Baer BR, Rettie AE. CYP4B1: an enigmatic P450 at the interface between xenobiotic and endobiotic metabolism. Drug Metab Rev 2006; 38:451-76.

Baer BR, Wienkers LC, Rock DA. Time-dependent inactivation of P450 3A4 by raloxifene: identification of Cys239 as the site of apoprotein alkylation. Chem Res Toxicol 2007; 20:954-64.

Bafica A, Scanga CA, Serhan C et al. Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. J Clin Invest 2005; 115:1601-6.

Baghdasaryan A, Claudel T, Kosters A et al. Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation. Gut 2010; 59:521-30.

Bagnoli F, de Oliveira VM, da Silva MA, Taromaru GC, Rinaldi JF, Aoki T. The interaction between aromatase, metalloproteinase 2,9 and CD44 in breast cancer. Rev Assoc Med Bras 2010; 56:472-7.

Bagriantsev S, Liebman S. Modulation of Aβ42 low-n oligomerization using a novel yeast reporter system. BMC Biol 2006; 4:32.

Baguley BC. Multiple drug resistance mechanisms in cancer. Mol Biotechnol 2010; 46:308-16.

Bah J, Quach H, Ebstein RP et al. Maternal transmission disequilibrium of the glutamate receptor GRIK2 in schizophrenia. Neuroreport 2004; 15:1987-91.

Bahadur N, Leathart JB, Mutch E et al. CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes. Biochem Pharmacol 2002; 64:1579-89.

Bahar AY, Taylor PJ, Andrews L et al. The frequency of founder mutations in the BRCA1, BRCA2, and APC genes in Australian Ashkenazi Jews: implications for the generality of U. S. population data. Cancer 2001; 92:440-5.

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Bahn A, Prawitt D, Buttler D et al. Genomic structure and in vivo expression of the human organic anion transporter 1 (hOAT1) gene. Biochem Biophys Res Commun 2000; 275:623-30.

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Bahrami F, Yousefpour M, Mehrani H et al. Type of cell death and the role of acetylcholinesterase activity in neurotoxicity induced by paraoxon in cultured rat hippocampal neurons. Acta Biol Hung 2009; 60:1-13.

Bai C, Matsui E, Ohnishi H et al. A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma. Int J Mol Med 2008; 21:139-44.

Bai N, Kido T, Suzuki H et al. Changes in atherosclerotic plaques induced by inhalation of diesel exhaust. Atherosclerosis 2011; 216:299-306.

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Bai Y, Yu Y, Yu B et al. Association of vitamin D receptor polymorphisms with the risk of prostate cancer in the Han population of Southern China. BMC Med Genet 2009; 10:125.

Bai YM, Chen TT, Liou YJ, Hong CJ, Tsai SJ. Association between HTR2C polymorphisms and metabolic syndrome in patients with schizophrenia treated with atypical antipsychotics. Schizophr Res 2011; 125:179-86.

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Bailey DG, Dresser GK, Bend JR. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clin Pharmacol Ther 2003; 73:529-37.

Bailey DG, Dresser GK, Kreeft JH, Munoz C, Freeman DJ, Bend JR. Grapefruit-felodipine interaction: effect of unprocessed fruit and probable active ingredients. Clin Pharmacol Ther 2000; 68:468-77.

Bailey DG, Dresser GK, Leake BF, Kim RB. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin Pharmacol Ther 2007; 81:495-502.

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Bailey KM, Romaine SP, Jackson BM et al. Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study. Circ Cardiovasc Genet 2010; 3:276-85.

Bailey LR, Roodi N, Dupont WD, Parl FF. Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer. Cancer Res 1998; 58:5038-41.

Bains OS, Karkling MJ, Grigliatti TA, Reid RE, Riggs KW. Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin. Drug Metab Dispos 2009; 37:1107-14.

Baird JK, Hoffman SL. Primaquine therapy for malaria. Clin Infect Dis 2004; 39:1336-45.

Baird PN, Guida E, Chu DT, Vu HT, Guymer RH. The epsilon2 and epsilon4 alleles of the apolipoprotein gene are associated with age-related macular degeneration. Invest Ophthalmol Vis Sci 2004; 45:1311-5.

Baitsch D, Bock HH, Engel T et al. Apolipoprotein e induces antiinflammatory phenotype in macrophages. Arterioscler Thromb Vasc Biol 2011; 31:1160-8.

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Baker AD, Malur A, Barna BP, Kavuru MS, Malur AG, Thomassen MJ. PPARgamma regulates the expression of cholesterol metabolism genes in alveolar macrophages. Biochem Biophys Res Commun 2010; 393:682-7.

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